Repair & recovery
BPC-157
A 15-amino-acid peptide linked to the movement and organization of cells involved in tissue repair.
Cell movement and tissue organization.
BPC-157 stands for Body Protection Compound 157. Laboratory work connects it with signals that help connective-tissue cells attach, move, and organize. These processes are part of how tissue responds to injury.
How it works.
- FAK–paxillin signaling
- In tendon fibroblast experiments, BPC-157 increased activation of these proteins involved in cell adhesion and movement.
- Cell migration
- Tendon fibroblasts exposed to BPC-157 moved more readily through their surroundings in culture.
- Tendon outgrowth
- Tendon tissue explants exposed to BPC-157 showed increased outgrowth of cells.
Useful terms
- Fibroblast
- A cell that produces and maintains connective tissue.
- FAK
- Focal adhesion kinase, a protein involved in cell attachment and movement.
- Explant
- A piece of tissue maintained outside the body for observation.
Results.
Risks, concerns & drawbacks.
- Side-effect information
- A separate two-person intravenous pilot reported no side effects during three days of checks. That small sample leaves uncommon reactions and repeated-use effects poorly characterized.
- Pain relief & tissue repair
- The knee report measured recalled pain relief. It did not use follow-up scans to measure tendon, ligament, or cartilage repair.