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@media(max-width:850px){.peptide-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.peptide-layout{grid-template-columns:1fr;gap:0}.peptide-sidebar{border-right:0;border-bottom:1px solid var(--line);padding:20px 0 17px}.sidebar-inner{position:static;max-height:none;overflow:visible;display:flex;flex-wrap:wrap;align-items:center;justify-content:space-between;gap:15px}.peptide-sidebar .back-link{margin:0}.peptide-sidebar>.sidebar-inner>.eyebrow{display:none}.index-toggle{display:flex;align-items:center;gap:12px;border:0;background:none;padding:5px 0;font-size:.875rem}#peptide-index{display:none;flex-basis:100%;padding-top:10px}#peptide-index.is-open{display:block}#peptide-index nav{display:grid;grid-template-columns:1fr 1fr;column-gap:35px}.sidebar-group a{margin-inline:0}.compound-hero{grid-template-columns:1fr 150px}.receptor-diagram{width:150px}.compound-hero h1{font-size:4rem}.compound-art{width:100px;height:100px}.library-bottom{align-items:flex-start;flex-direction:column}}
@media(max-width:550px){.library-tools{gap:12px;flex-wrap:wrap;margin-bottom:20px}.library-tools .search-field{flex-basis:100%}.result-count{margin-left:0}.search-field input{font-size:.9375rem}.filters{gap:8px;margin-bottom:23px}.filters button{font-size:.8125rem;padding:8px 11px}.peptide-grid{grid-template-columns:1fr;gap:15px}.peptide-card{min-height:212px;padding:23px}.peptide-card h2{font-size:2.15rem}.card-top{margin-bottom:12px}.card-top .eyebrow{font-size:.6875rem;max-width:none}.library-bottom{padding-block:30px;margin-top:28px}.library-bottom h2{font-size:2rem}.compound-hero{grid-template-columns:1fr 65px;gap:12px;padding-bottom:25px}.compound-hero h1{font-size:clamp(2.4rem,9.4vw,3.5rem)}.compound-hero .lede{font-size:1rem;grid-column:1/-1}.compound-art{width:60px;height:60px}.receptor-diagram{width:74px}.compound-hero>div{display:contents}.compound-hero .eyebrow{grid-column:1/-1}.compound-hero h1{grid-column:1;margin:0}.compound-hero>.compound-art,.compound-hero>.receptor-diagram{grid-column:2;grid-row:2}.page-tabs{gap:15px 20px;font-size:.8125rem}.compound-section{padding-block:26px}.compound-section h2{font-size:1.95rem}.mechanism-list>div{grid-template-columns:1fr;gap:5px;padding:13px 0}.term-list{grid-template-columns:1fr}.related-grid{grid-template-columns:1fr;gap:20px}.related-grid a+a{border-left:0;padding-left:0;border-top:1px solid var(--line);padding-top:20px}.related-grid a+a .icon{top:28px}.peptide-pagination{gap:15px}.peptide-pagination a{font-size:.8125rem;gap:7px}.peptide-pagination small{font-size:.6875rem}.breadcrumb{font-size:.8125rem;gap:8px}.peptide-content .breadcrumb{margin-bottom:24px}.sidebar-group .eyebrow{font-size:.6875rem}.sidebar-group a{font-size:.875rem;padding-left:8px}.source-links{gap:12px 20px}.source-links a{font-size:.8125rem}}
.comic-section{padding:30px 0 40px;border-top:1px solid var(--line)}.comic-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:30px}.comic-grid img{width:100%;aspect-ratio:1;object-fit:contain;mix-blend-mode:multiply}.comic-grid figcaption{text-align:center;margin-top:8px;font-size:.9375rem}.about-lead{display:grid;grid-template-columns:1fr 1.25fr;gap:70px;padding-block:40px}.about-lead h2{max-width:450px}.about-lead p{font-size:1.13rem}.beyond-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:32px 40px;margin-top:28px}.beyond-grid h3{font-size:1.65rem;margin-bottom:10px}.contact-section{display:flex;justify-content:space-between;gap:35px;align-items:center;padding-bottom:45px}.contact-section h2{margin:12px 0}.contact-email{display:inline-flex;gap:17px;align-items:center;font-size:1.25rem;margin-top:20px}.coming-soon{display:block;font-size:.8125rem;color:var(--muted);margin-top:5px}.document-grid{display:grid;grid-template-columns:1fr 1fr;gap:50px;padding:10px 0 40px}.document{border-top:1px solid var(--line);padding-top:25px;min-width:0}.document h2{font-size:2.6rem;margin:15px 0;max-width:520px}.document-actions{display:flex;align-items:center;gap:22px;margin:5px 0 30px}.document-actions .text-link{margin-top:22px;font-size:.875rem}.chapter-list{border-block:1px solid var(--line)}.chapter-list summary{display:flex;justify-content:space-between;gap:20px;cursor:pointer;list-style:none;padding:18px 0;font-size:.9375rem}.chapter-list summary::-webkit-details-marker{display:none}.chapter-list[open] summary .icon{transform:rotate(180deg)}.chapter-list ol{list-style:none;padding:0;margin:0 0 12px}.chapter-list li a{display:grid;grid-template-columns:24px 1fr 18px;gap:12px;padding:10px 0;border-top:1px solid var(--line);font-size:.875rem}.chapter-number{color:var(--muted);font-size:.75rem;padding-top:2px}.chapter-list li .icon{width:17px;height:17px}.learning-groups .resource-row h3{font-size:1.55rem}.learning-groups .resource-row:first-child{border-top:0;padding-top:0}
@media(max-width:850px){.about-lead{gap:35px}.beyond-grid{grid-template-columns:1fr 1fr}.document-grid{gap:32px}.document h2{font-size:2.2rem}.document-actions{align-items:flex-start;flex-direction:column;gap:15px}.document-actions .text-link{margin:0}.comic-grid{gap:18px}.contact-section{align-items:flex-start}}
@media(max-width:550px){.comic-grid{grid-template-columns:1fr 1fr;gap:25px 16px}.comic-grid figcaption{font-size:.875rem}.about-lead{grid-template-columns:1fr;gap:25px;padding-block:28px}.about-lead p{font-size:1rem}.beyond-grid{grid-template-columns:1fr;gap:24px}.contact-section{flex-direction:column}.contact-email{font-size:1rem;gap:9px;overflow-wrap:anywhere}.document-grid{grid-template-columns:1fr;gap:35px}.document h2{font-size:2.15rem}.document-actions{flex-direction:row;align-items:center;gap:20px}.document-actions .text-link{margin-top:22px}}

.guide-opening{border-top:0;border-bottom:1px solid var(--line);padding-top:32px}.guide-opening .page-intro{padding:0 0 25px}.guide-intro h2{margin-bottom:15px}.guide-intro{padding-block:36px}
@media(max-width:550px){.guide-opening{padding-top:26px;padding-bottom:28px}.guide-opening .page-intro{padding-bottom:20px}.guide-intro{padding-block:28px}}

/* Direct homepage directory and matching editorial line art. */
.hero-illustration{margin:0;align-self:center}.hero-illustration img{width:100%;aspect-ratio:1.5;object-fit:contain;mix-blend-mode:multiply}.home-directory{padding:38px 0 43px;border-bottom:1px solid var(--line);scroll-margin-top:28px}.home-directory .section-heading{margin-bottom:24px;align-items:end}.home-directory .section-heading h2{margin-top:8px}.home-directory .section-heading>p{font-size:.85rem}.home-peptide-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px}.home-peptide{display:flex;align-items:center;gap:18px;min-height:108px;padding:22px 20px;border:1px solid var(--line);background:#f5f2eb;transition:background .18s,border-color .18s}.home-peptide:hover{background:#e8e1d5;border-color:#94816b;color:var(--ink)}.home-peptide>.icon:first-child{width:31px;height:31px;color:#9c866a;stroke-width:1}.home-peptide>div{flex:1;min-width:0}.home-peptide h3{font-size:1.48rem;line-height:1.18}.home-peptide p{font-size:.75rem;line-height:1.5;margin-top:7px}.home-peptide>.icon:last-child{width:17px;height:17px;color:#786c5b}.home-directory .section-heading h2{font-size:2.5rem}
@media(max-width:1100px){.home-peptide-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.home-peptide{min-height:104px}.home-hero{gap:24px}.hero-illustration{max-width:510px}}
@media(max-width:650px){.home-peptide-grid{grid-template-columns:1fr}.home-directory .section-heading{display:block}.home-directory .section-heading>p{margin-top:12px}.home-directory .section-heading h2{font-size:2.25rem}.home-peptide{min-height:93px;padding:17px 20px}.home-peptide h3{font-size:1.55rem}.hero-illustration{max-width:340px;margin:0 auto}.home-hero{padding-bottom:25px}.home-peptide p{font-size:.8rem}}

.prick-feature .prick-nonprofit{font-size:.88rem;margin-top:9px}

/* Keep every editorial column within the available page width. */
body:not(.texasprick-site) .shell{width:calc(100% - clamp(36px,6vw,80px));max-width:1200px}
body:not(.texasprick-site) main{min-width:0}
body:not(.texasprick-site) :is(section,article,aside,figure,nav,header,footer,div){min-width:0}
body:not(.texasprick-site) :is(h1,h2,h3,p,dd,dt,a){overflow-wrap:anywhere}
body:not(.texasprick-site) .site-header{gap:36px;min-height:100px}
body:not(.texasprick-site) .site-header nav{width:auto;flex:1;min-width:0;margin-left:0;justify-content:flex-end;gap:clamp(18px,2.5vw,32px)}
body:not(.texasprick-site) .site-header .brand{width:155px}
body:not(.texasprick-site) .nav-contact{margin-left:18px}
.home-hero{grid-template-columns:minmax(0,.95fr) minmax(0,1.25fr);gap:42px;padding:44px 0;align-items:center}
.home-hero h1{font-size:clamp(2.35rem,3.8vw,3.4rem);line-height:1.07;letter-spacing:-.035em;margin:16px 0 22px}
.home-hero .lede{font-size:1.08rem;max-width:38ch}
.ember-photo{margin:0;min-width:0;background:#2a241e}
.ember-photo img{width:100%;height:auto;aspect-ratio:1672/941;object-fit:contain;display:block}
.pathways{grid-template-columns:repeat(3,minmax(0,1fr));padding-block:28px}
.pathway{gap:18px;padding-inline:24px}
.pathway>.icon{width:44px;height:44px}
.pathway h2{font-size:1.42rem}
.pathway p{font-size:.93rem}
.home-directory{padding:40px 0}
.home-peptide-grid{gap:14px}
.home-peptide{padding:20px 17px;gap:14px}
.home-peptide h3{font-size:1.35rem}
.home-peptide p{font-size:.82rem}
.prick-feature.photo-feature{grid-template-columns:minmax(0,1.15fr) minmax(0,1fr);align-items:center;gap:44px;padding:44px 0}
.photo-feature .prick-brand{width:230px;max-width:100%;margin:0 0 10px}
.photo-feature h2{font-size:clamp(2rem,3vw,2.7rem)}
.photo-feature p{font-size:1rem;max-width:43ch}
.photo-feature .text-link{margin-top:8px}
.mission-feature{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,.8fr);gap:60px;align-items:center;padding:38px 0}
.mission-feature h2{font-size:clamp(2rem,3vw,2.7rem);max-width:19ch}
.mission-feature p{font-size:1rem;max-width:52ch}
.mission-illustration img{width:100%;height:auto;mix-blend-mode:multiply}
.page-intro.with-photo{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1.1fr);align-items:center;gap:44px;padding-bottom:45px}
.page-intro.with-photo h1{font-size:clamp(2.5rem,4vw,3.7rem)}
.page-intro.with-photo .lede{font-size:1.12rem}
.page-intro.with-art{grid-template-columns:minmax(0,1fr) 150px}
.columns{grid-template-columns:repeat(3,minmax(0,1fr))}
.reading-content .columns{grid-template-columns:repeat(2,minmax(0,1fr))}
.mechanism-list>div{grid-template-columns:180px minmax(0,1fr)}
.term-list,.related-grid,.document-grid{grid-template-columns:repeat(2,minmax(0,1fr))}
.about-lead{grid-template-columns:minmax(0,1fr) minmax(0,1.25fr)}
.beyond-grid{grid-template-columns:repeat(3,minmax(0,1fr))}
.peptide-pagination>a{flex:1;min-width:0}
.peptide-pagination>a:last-child{justify-content:flex-end}
.site-footer{grid-template-columns:145px minmax(0,1.3fr) repeat(2,minmax(0,1fr));gap:28px}
.site-footer>div,.site-footer>.download{padding-left:24px;min-width:0}
.site-footer>div>a{overflow-wrap:anywhere}
@media(max-width:1000px){
 .home-hero{grid-template-columns:minmax(0,1fr);gap:28px;padding-top:32px}
 .home-hero h1{font-size:clamp(2.3rem,5.5vw,3.4rem)}
 .home-hero .lede{max-width:52ch}
 .home-hero .ember-photo{width:100%}
 .prick-feature.photo-feature{gap:28px}
 .mission-feature{gap:32px}
 .page-intro.with-photo{grid-template-columns:minmax(0,1fr);gap:28px}
 .page-intro.with-photo h1{max-width:22ch}
 .page-intro.with-photo .lede{max-width:60ch}
 .site-footer{grid-template-columns:145px minmax(0,1fr)}
 .site-footer>.download{border-left:0;border-top:1px solid var(--line);padding:18px 0 0}
}
@media(max-width:850px){
 body:not(.texasprick-site) .site-header{gap:0;min-height:88px}
 body:not(.texasprick-site) .site-header nav{flex-basis:100%;margin:0;gap:0}
 body:not(.texasprick-site) .nav-contact{margin-left:0}
 .page-intro.with-art{grid-template-columns:minmax(0,1fr) 90px}
 .compound-hero{grid-template-columns:minmax(0,1fr) 120px}
 .receptor-diagram{max-width:100%;height:auto}
 .mission-feature{grid-template-columns:minmax(0,1fr) minmax(0,.65fr);gap:24px}
 .beyond-grid{grid-template-columns:repeat(2,minmax(0,1fr))}
 .contact-section{flex-wrap:wrap}
}
@media(max-width:700px){
 .prick-feature.photo-feature{grid-template-columns:minmax(0,1fr);gap:26px;padding:32px 0}
 .pathways{grid-template-columns:minmax(0,1fr);padding:0}
 .pathway{display:flex;padding:23px 0!important;gap:20px}
 .pathway+.pathway{border-left:0;border-top:1px solid var(--line)}
 .pathway>.icon{margin:0;align-self:center}
 .pathway h2{font-size:1.45rem}
 .mission-feature{grid-template-columns:minmax(0,1fr);gap:20px;padding-block:32px}
 .mission-illustration{max-width:330px;justify-self:center}
 .columns{grid-template-columns:minmax(0,1fr)}
 .about-lead{grid-template-columns:minmax(0,1fr);gap:24px}
}
@media(max-width:550px){
 .home-hero{padding-top:26px;gap:25px}
 .home-hero h1{font-size:clamp(2rem,8.5vw,2.85rem);letter-spacing:-.035em}
 .home-hero .lede,.page-intro.with-photo .lede{font-size:1rem}
 .home-directory .section-heading h2{font-size:2rem}
 .home-peptide h3{font-size:1.4rem}
 .page-intro.with-art{grid-template-columns:minmax(0,1fr) 60px}
 .page-intro.with-photo{gap:24px;padding-bottom:30px}
 .page-intro.with-photo h1{font-size:2.5rem}
 .reading-content .columns,.term-list,.related-grid,.document-grid,.beyond-grid{grid-template-columns:minmax(0,1fr)}
 .compound-hero{grid-template-columns:minmax(0,1fr) 65px}
 .mechanism-list>div{grid-template-columns:minmax(0,1fr)}
 .document-actions{flex-wrap:wrap;gap:14px}
 .contact-email{max-width:100%;font-size:clamp(.88rem,4vw,1rem);gap:7px}
 .site-footer{grid-template-columns:minmax(0,1fr);gap:18px;padding-top:28px}
 .site-footer>div{padding-left:0;border-left:0;font-size:.9rem}
 .site-footer>.download{font-size:.88rem}
 .site-footer>.brand{width:140px}
 .section-heading h2{overflow-wrap:anywhere}
}